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Phenethylamines [& Tryptamines] I Have Known And Loved (1991, [1997])

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Alexander Theodore Shulgin was an American medicinal chemist, biochemist, organic chemist, pharmacologist, psychopharmacologist, and author. He is credited with introducing MDMA ("ecstasy", "mandy" or "molly") to psychologists in the late 1970s for psychopharmaceutical use and for the discovery, synthesis and personal bioassay of over 230 psychoactive compounds for their psychedelic and entactogenic potential.

In 1991 and 1997, he and his wife Ann Shulgin compiled the books PIHKAL and TIHKAL (standing for Phenethylamines and Tryptamines I Have Known And Loved), from notebooks which extensively described their work and personal experiences with these two classes of psychoactive drugs. Shulgin performed seminal work into the descriptive synthesis of many of these compounds. Some of Shulgin's noteworthy discoveries include compounds of the 2C* family (such as 2C-B) and compounds of the DOx family (such as DOM).

Due in part to Shulgin's extensive work in the field of psychedelic research and the rational drug design of psychedelic drugs, he has since been dubbed the "godfather of psychedelics"

These texts are difficult to read. Some are scanned but the text doesn't always read properly. If you have correct and complete scans, please share.


Thanks a lot for sharing these. These are both massive books. I remember finding a brand new copy of TIHKAL in Vancouver at a store called The Urban Shaman for 20 bucks, marked down from 50 or so. But I gave it away to a friend who was interested in making (and doing) drugs.

I found an epub version of TIHKAL that is just the text and not the full scans like from the pdf here:

Cheers, that file is *much* easier to read. I really appreciate your sharing it!

so, if I am understanding all of this correctly, phenethylamines, tryptamines, and ergolines can all produce hallucinogenic experiences. given that I am philosophically inclined toward tryptamines, what might the advantages of the other chemicals be compared with tryptamines? are there side effects or blindspots associated with tryptamines that the others avoid or cut through?

I guess another way to look at this is that there are 10,000 different states of experiencing this inglorious matrix and, while I am partial to the class of states engendered by tryptamines, I cannot and should not discount the value and validity of the others.

is there anyone here who prefers the others? PKD really seemed to value amphetamines, and there is an argument to be made that non only all of his work is the product of that state of mind, but his paranoia, too, might have been a natural outgrowth of it.

happy to be persuaded otherwise...