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First Synthetic Lifeform is Nigh
12-01-2008, 02:11 PM, (This post was last modified: 12-01-2008, 02:12 PM by ---.)
#1
First Synthetic Lifeform is Nigh
June 2007


Quote:Exciting scientific developments descend upon us, as scientists at the J Craig Venter Institute in Rockville, Maryland, have successfully managed to transfer an entire genome of one species into another — which grew and multiplied into the first species. Why is this significant? Because the next experiment involves creating and implanting a synthetic genome — the success of which could mark the creation of the first artificial lifeform and enable greater possibilities for biological engineering.

The achievement was made today by Dr. Craig Venter and his team using the following method as described in their press release:

The JCVI team devised several key steps to enable the genome transplantation. First, an antibiotic selectable marker gene was added to the M. mycoides LC chromosome to allow for selection of living cells containing the transplanted chromosome. Then the team purified the DNA or chromosome from M. mycoides LC so that it was free from proteins (called naked DNA). This M. mycoides LC chromosome was then transplanted into the M. capricolum cells. After several rounds of cell division, the recipient M. capricolum chromosome disappeared having been replaced by the donor M. mycoides LC chromosome, and the M. capricolum cells took on all the phenotypic characteristics of M. mycoides LC cells.

Colonies of the transformed Mycoplasma mycoides bacterium
[Image: transplanted_cells_large.gif]
The image above shows colonies of the transformed Mycoplasma mycoides bacterium. Dr. Venter says that in light of this advance — the team plans to do the same using a genome produced from scratch in a laboratory within months. As reported by the UK Telegraph:

The scientists want to create new kinds of bacterium to make new types of bugs which can be used as green fuels to replace oil and coal, digest toxic waste or absorb carbon dioxide and other greenhouse gases from the atmosphere.

[...]

Since the 1970s, scientists have moved genes - instructions to make proteins - between different organisms.

But this marks the first time that the entire instruction set, consisting of more than a million “letters” of DNA, has been transplanted, transforming one species of bacterium into another.

They are attempting to build a microbe with the minimal set of genes needed for life, with the goal of then adding other useful genes, such as ones for making biofuels.

Seems my simulated artificial lifeforms don’t seem as significant for the time being! But of course, there are still things that we need to overcome. According to the Telegraph, only one in every 150,000 transfers worked. There are also concerns regarding safety — unexpected side effects can abruptly become evident when evolution is superseded. Venter mentions in addition that the project was on pause for some time while under review for ethical concerns, as these advances can lead to new kinds of biological warfare.

Nevertheless it’s an exciting development and I look forward to hearing the results of their consequent experiments.

http://www.thinkartificial.org/technology/...-nigh/#more-348
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12-06-2008, 12:37 PM, (This post was last modified: 12-06-2008, 12:37 PM by JazzRoc.)
#2
First Synthetic Lifeform is Nigh
What we need is a microbe that converts sunlight, water, and CO2 into gasoline. Inside a solar panel.
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12-06-2008, 02:13 PM,
#3
First Synthetic Lifeform is Nigh
As vonnegut pointed out, we're petroleum junkies
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12-06-2008, 08:11 PM,
#4
First Synthetic Lifeform is Nigh
Quote:Nevertheless it’s an exciting development and I look forward to hearing the results of their consequent experiments.
I'm not excited about it.

what existing life forms will have to compete with the artifical ones ?
&Alice laughed, &There's no use trying,& she said: &one can't believe impossible things.& &I daresay you haven't had much practice,& said the Queen. &When I was your age I always did it for half-an-hour a day. Why, I've believed as many as six impossible things before breakfast.&
- Lewis Carroll

&Things are seldom as they seem ... Skim milk masquerades as cream.&
- Gilbert and Sullivan (Pinafore)

At NASA, it really is rocket science, and the decision makers really are rocket scientists.
But a body of research that is getting more and more attention points to the ways that smart people working collectively can be dumber than the sum of their parts. .. Irwin Janis? &Groupthink:& is a mode of thinking that people engage in when they are deeply involved in a cohesive in-group, when the members' striving for unanimity override realistic appraisals ? It is the triumph of concurrence over good sense, and authority over expertise.&
-John Schwartz & Matthew L. Wade
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12-06-2008, 08:17 PM,
#5
First Synthetic Lifeform is Nigh
Quote:
Quote:Nevertheless it’s an exciting development and I look forward to hearing the results of their consequent experiments.
I'm not excited about it.

what existing life forms will have to compete with the artifical ones ?

'Quote: nik' I never said that! LOL

All of them.


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12-06-2008, 08:59 PM,
#6
First Synthetic Lifeform is Nigh
Quote:
Quote:
Quote:Nevertheless it’s an exciting development and I look forward to hearing the results of their consequent experiments.
I'm not excited about it.

what existing life forms will have to compete with the artifical ones ?

'Quote: nik' I never said that! LOL

All of them.
no you didn't, the article did
&Alice laughed, &There's no use trying,& she said: &one can't believe impossible things.& &I daresay you haven't had much practice,& said the Queen. &When I was your age I always did it for half-an-hour a day. Why, I've believed as many as six impossible things before breakfast.&
- Lewis Carroll

&Things are seldom as they seem ... Skim milk masquerades as cream.&
- Gilbert and Sullivan (Pinafore)

At NASA, it really is rocket science, and the decision makers really are rocket scientists.
But a body of research that is getting more and more attention points to the ways that smart people working collectively can be dumber than the sum of their parts. .. Irwin Janis? &Groupthink:& is a mode of thinking that people engage in when they are deeply involved in a cohesive in-group, when the members' striving for unanimity override realistic appraisals ? It is the triumph of concurrence over good sense, and authority over expertise.&
-John Schwartz & Matthew L. Wade
Reply
12-06-2008, 09:35 PM,
#7
First Synthetic Lifeform is Nigh
Quote:
Quote:
Quote:
Quote:Nevertheless it’s an exciting development and I look forward to hearing the results of their consequent experiments.
I'm not excited about it.

what existing life forms will have to compete with the artifical ones ?

'Quote: nik' I never said that! LOL

All of them.
no you didn't, the article did

I know. You could just cut and paste from the article and wrap it in quote tags so it doesn't appear to quote directly..it's something in nothing. no worries:)
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12-06-2008, 10:07 PM,
#8
First Synthetic Lifeform is Nigh
This experimentation can definitely go out of hand.
[Image: Palestinian_Dawn_by_Palestinian_Pride.jpg]
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01-03-2009, 11:40 PM,
#9
First Synthetic Lifeform is Nigh
hordes of gasoline producing vampire leeches that feed off the blood and sweat of humans all over the world.....now that what we need! i think they just added that bio fuels reference to take the eyes of the onlookers away from the development of the biological warfare that could arise from this
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