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Study: Cannabis Use Unlikely To Cause Schizophrenia
12-20-2013, 06:41 AM,
#1
Study: Cannabis Use Unlikely To Cause Schizophrenia
A strong counterpoint to the propaganda that cannabis use causes mental illness including schizophrena...

Quote:Study: Cannabis Use Unlikely To Cause Schizophrenia

Boston, MA: Family genetics, rather than adolescent cannabis use, increases risk of schizophrenia, according to a case control study published online in the journal Schizophrenia Research.

Investigators from Harvard Medical School compared the family histories of 108 schizophrenia patients and 171 individuals without schizophrenia to assess whether youth cannabis consumption was an independent factor in developing the disorder. Researchers reported that a family history of schizophrenia increased the risk of developing the disease, regardless of whether or not subjects consumed cannabis as adolescents.

"There was an increased morbid risk for schizophrenia in relatives of the cannabis using and non-using patient samples compared with their respective non-psychotic control samples," authors reported. "There was no significant difference in morbid risk for schizophrenia between relatives of the patients who use or do not use cannabis."

They concluded: "The results of the current study, both when analyzed using morbid risk and family frequency calculations, suggest that having an increased familial risk for schizophrenia is the underlying basis for schizophrenia in these samples and not the cannabis use. While cannabis may have an effect on the age of onset of schizophrenia it is unlikely to be the cause of illness."

Previous studies have reported that rates of schizophrenia have remained steady for decades despite changing patterns in cannabis use among the population.

Commenting on the study's findings, NORML Deputy Director Paul Armentano said: "Concerns regarding cannabis' potential impact on psychiatric illnesses arguably warrant further study. However, such concerns - even if confirmed - are not persuasive justifications for continuing cannabis criminalization. Just the opposite is true. There are numerous adverse health consequences associated with alcohol, tobacco and prescription drugs, all of which are far more dangerous and costlier to society than cannabis. It is precisely because of these consequences that these products are legally regulated and their consumption is restricted to specified consumers and settings. This same principle ought to apply to cannabis."

For more information, please contact Paul Armentano, NORML Deputy Director, at: paul@norml.org. Full text of the study, "A controlled family study of cannabis users with and without psychosis," appears in Neuropsychopharmacology
.

Quote:Study: Cannabidiol Holds Promise For Treating Psychosis

Utrecht, The Netherlands: Cananbidiol (CBD), a non-psychotropic cannabinoid, alleviates psychotic symptoms and may hold promise as an alternative antipsychotic treatment, according to a review published in the November issue of the journal Neuropsychopharmacology.

Investigators in the Netherlands and in the United Kingdom reviewed preclinical and clinical data on the use of CBD as an antipsychotic agent. Authors reported that both animal and human studies document the ability of CBD to mitigate symptoms of psychosis. Specifically, CBD administration is associated with improved symptoms in clinical evaluations of patients with schizophrenia, Parkinson's disease, and ketamine-induced dissociative and psychotic symptoms.

Investigators also highlighted a 2012 double-blind, randomized placebo-controlled trial assessing CBD versus the prescription anti-psychotic drug amisulpride in 42 subjects with schizophrenia and acute paranoia. Authors reported that both CBD and the prescription drug were associated with "equally significant clinical improvement" in this patient population, but that cannabidiol "possessed significantly less side effects."

They concluded: "[E]vidence from several study domains suggests that CBD has some potential as an antipsychotic treatment. ... Given the high tolerability and superior cost-effectiveness, CBD may prove to be an attractive alternative to current antipsychotic treatment."

Previous human trials assessing the administration of CBD in healthy human subjects report that the cannabinoid is "safe and well tolerated."

Separate investigations of CBD, primarily in animal models, have documented the cannabinoid to possess a variety of therapeutic qualities, including anti-inflammatory, anti-diabetic, anti-epileptic, anti-cancer, and bone-stimulating properties. Recently, the FDA approved the experimental use of CBD extracts for the treatment of a rare form of intractable pediatric epilepsy known as Dravet syndrome. Preliminary clinical trials assessing the safety and tolerability of the compound in children are scheduled to begin imminently.

For more information, please contact Paul Armentano, NORML Deputy Director, at: paul@norml.org. Full text of the study, "Cannabidiol as a potential treatment for psychosis," appears in Neuropsychopharmacology.
“Today’s scientists have substituted mathematics for experiments, and they wander off through equation after
equation, and eventually build a structure which has no relation to reality. ” -Nikola Tesla

"When the power of love overcomes the love of power the world will know peace." -Jimi Hendrix
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12-20-2013, 04:36 PM,
#2
RE: Study: Cannabis Use Unlikely To Cause Schizophrenia
If it was true, with the amount of weed Ive smoked in my lifetime, I'd be a Schizo 10 times over.
"Listen to everyone, read everything, believe nothing unless you can prove it in your own research"
~William Cooper

DTTNWO!
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12-21-2013, 11:14 AM,
#3
RE: Study: Cannabis Use Unlikely To Cause Schizophrenia
Hmmm ...weve all heard of the elderly relative who smoked for 50 years and didnt get lung cancer and the heavy drinker who still has a reasonable liver.
Quote:While cannabis may have an effect on the age of onset of schizophrenia it is unlikely to be the cause of illness
That seems to suggest that at the very least it has a contributory effect.
Also is a study of around 200 selected individuals conclusive?
Jurys still out I think on this one...
Remember you are unique
...just like everyone else.
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12-21-2013, 06:41 PM,
#4
RE: Study: Cannabis Use Unlikely To Cause Schizophrenia
(12-20-2013, 04:36 PM)SiLVa Wrote: If it was true, with the amount of weed Ive smoked in my lifetime, I'd be a Schizo 10 times over.

We, uh, I mean I am in the same boat.
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12-22-2013, 03:32 AM,
#5
RE: Study: Cannabis Use Unlikely To Cause Schizophrenia
(12-21-2013, 11:14 AM)Swordfish Wrote: Hmmm ...weve all heard of the elderly relative who smoked for 50 years and didnt get lung cancer and the heavy drinker who still has a reasonable liver.
Quote:While cannabis may have an effect on the age of onset of schizophrenia it is unlikely to be the cause of illness
That seems to suggest that at the very least it has a contributory effect.
Also is a study of around 200 selected individuals conclusive?
Jurys still out I think on this one...
If someone has a predisposition to anything.. then pretty much anything can trigger it.
this is as true of psychological disorders as it is for the likes of cancer.
now, here's a thing.. i have a friend in Glasgow.. his mother..Schizophrenic.. his brother.. the same..
He smokes not weed but hash and only 1 particular type of hash... soft black.
the reason... he is also predisposed to schizophrenia and has had a couple of episodes in his youth.
He has been smoking this particular type of has as it's VERY high in CBD content... lots of CBD gives you that "heavy mong" stone (smokers will know what i mean)
the guy doesn't take any other meds any more after being advised about it by a guy that works at Aberdeen university researching canabanoids. we have known the guy for years from the Goth/industrial scene and he's a very smart cookie.
for him it's daily medication.. he doesn't get stoned like most people would who are occasional smokers. for him it's something he does 4 times a day and it keeps him steady and on an even keel and happily working with no probs any more.
[Image: siolflag.gif]
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12-22-2013, 03:57 AM,
#6
RE: Study: Cannabis Use Unlikely To Cause Schizophrenia
Well, CBD itself is non-psychoactive and anti-schizophrenic. It interacts with THC and the other cannabinoids to produce heavy body effects like relaxation and pain mitigation. There have been some folks creating extracts that are approaching pure CBD and no THC that are used as medicine for children with terrible epilepsy. It brings those kids around to almost normal immediately. Amazing compounds from an amazing plant.
“Today’s scientists have substituted mathematics for experiments, and they wander off through equation after
equation, and eventually build a structure which has no relation to reality. ” -Nikola Tesla

"When the power of love overcomes the love of power the world will know peace." -Jimi Hendrix
Reply


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