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Scientists create technique to delete traumatic memories
11-02-2010, 04:32 PM,
Scientists create technique to delete traumatic memories
Quote:Researchers have found a way of permanently deleting painful memories, which they say could lead to drugs for post-traumatic stress disorder.

A team at John Hopkins University in the U.S removed a protein from the region of the brain responsible for recalling fear in tests on mice.

The mice were then unable to recall fear associated with a loud sound.

The method is similar to that imagined in the film Eternal Sunshine Of The Spotless Mind, where Jim Carrey and Kate Winslet decide to erase each other from their memories after a difficult break-up.

The scientists, whose report appears in Science Express, said it had important implications for patients whose lives were blighted by fear.

Lead researcher, Dr Richard L Huganir, said: 'When a traumatic event occurs, it creates a fearful memory that can last a lifetime and have a debilitating effect on a person’s life.

'Our finding describing these molecular and cellular mechanisms involved in that process raises the possibility of manipulating those mechanisms with drugs to enhance behavioural therapy for such conditions as post-traumatic stress disorder.'

Behavioural therapy has been shown to ease the depth of the emotional response to traumatic memories, but not in completely removing the memory itself, making relapse common.

Dr Huganir and post-doctoral fellow Roger Clem focused on the nerve circuits in the amygdala, the part of the brain known to underly so-called fear conditioning in people and animals.

Using sound to cue fear in mice, they observed that certain cells in the amygdala conducted more current after the mouse was exposed to a loud, sudden tone.

They found temporary increases in the amount of particular proteins - the calcium-permeable AMPARs - within a few hours of fear conditioning that peaked at 24 hours and disappeared 48 hours later.

These particular proteins are uniquely unstable and can be removed from nerve cells.

Dr Huganir said: 'The idea was to remove these proteins and weaken the connections in the brain created by the trauma, thereby erasing the memory itself.'

In further experiments, they found that removal of these proteins depended on the chemical modification of the GluA1 protein.

Mice lacking this chemical modification of GluA1 recovered fear memories induced by loud tones, whereas litter mates did not recover the same fear memories.

Dr Huganir suggests that drugs designed to control and enhance the removal of calcium-permeable AMPARs may be used to improve memory erasure.

Dr Huganir said: 'This may sound like science fiction, the ability to selectively erase memories.

'But this may one day be applicable for the treatment of debilitating fearful memories in people, such as post-traumatic stress syndrome associated with war, rape or other traumatic events.'

This study was funded by the National Institutes of Health and the Howard Hughes Medical Institute.
The revolution is not an apple that falls when it is ripe. You have to make it fall. - Che Guevara

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11-02-2010, 11:52 PM,
RE: Scientists create technique to delete traumatic memories
I'm going to assume this class of drugs works as well as most of the other crap they put out these days - not at all, with plenty of nasty side effects.

If it did work, big brother will use it on their soldiers and top secret workers.

Do I sound cynical? Maybe I have Oppositional Defiant Disorder.
[Image: randquote.png]
11-03-2010, 12:59 AM, (This post was last modified: 11-03-2010, 01:00 AM by icosaface.)
RE: Scientists create technique to delete traumatic memories
Good call yeti. We don't play hardball we play oddball.
An error does not become truth by reason of multiplied propagation, nor does truth become error because nobody sees it.
Mohandas Gandhi

Each of us is put here in this time and this place to personally decide the future of humankind.
Did you think you were put here for something less?
Chief Arvol Looking Horse
11-03-2010, 06:00 AM,
RE: Scientists create technique to delete traumatic memories
Forever trying to mess with the mind through the use of patented chemical concoctions, it's total madness. Why diet (what a person is putting into their "vehicle") is not the very first thing that is addressed in any and all illness I don't know. It's totally mad. I have seen people recover SO fast from really bad situations psychologically by simply ensuring they are getting good doses of nutrients, sometimes large doses in the first few days.

Yet big pharma keeps on rolling...
"He that saith he abideth in him ought himself also so to walk, even as he walked." -- 1 John 2:6
"Whatever affects one directly, affects all indirectly... This is the interrelated structure of reality." -- Martin Luther King Jr.
"He that answereth a matter before he heareth it, it is folly and shame unto him." -- Proverbs 18:13
"Everyone thinks of changing the world, but no one thinks of changing himself." -- Leo Tolstoy
"To love is to be vulnerable" -- C.S Lewis

The Kingdom of God is within you! -- Luke 17:20-21
11-03-2010, 10:09 PM,
RE: Scientists create technique to delete traumatic memories
Marketing Connections in Film:

Eternal Sunshine of the Spotless Mind
Strange Days
Total Recall
The Bourne Ultimatum
50 First Dates
Vanilla Sky (Open Your Eyes / Abre los Ojos)
Code Geass: Lelouch of the Rebellion

Suicide / Euthanasia / Abortion / Murder / Slow Kill Eugenics : Time factor aside these are akin to erasing or totally denying, erasing or deleting future experience.

Heavy Trauma, Some Psychologists, Drugs/Chemicals/Hormones, Frequencies (EM, Microwaves?), Hypnotic Regression and Alzheimers (Heavy Metals) can really mess it up too.
There are no others, there is only us.
11-04-2010, 12:46 AM,
RE: Scientists create technique to delete traumatic memories
this could only be of any use in VERY extreeme cases. its not like you can just decide to rid yourself of fear. can you imagine walking around your life unafraid of anything? fear is a part of life.

This cannot be targetted to individual memories. useless in a majority of cases. perhaps shell shock at the most. nervous trauma victims may have some sort of treatment. i cant see this getting all that far. drugs are not targetable unless ignoring all but one common element. fail.

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