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Over 2,500 Subjects Since 2005 Have Used Marijuana-Based Medicines In Controlled Clin
02-27-2010, 12:27 AM,
#1
Over 2,500 Subjects Since 2005 Have Used Marijuana-Based Medicines In Controlled Clin
Quote:Over 2,500 Subjects Since 2005 Have Used Marijuana-Based Medicines In Controlled Clinical Trials

Hurth, Germany:
Researchers worldwide have performed 37 separate clinical trials assessing the therapeutic safety and efficacy of inhaled cannabis and marijuana-based medicines since 2005, according to a review published online last week in the journal Cannabinoids: The Journal of the International Association for Cannabinoid Medicines (IACM).

Investigators from Leiden University in the Netherlands and the nova-Institut in Germany conducted a systematic review of recent clinical trial data pertaining to the medical use of whole smoked marijuana and cannabinoids.

Authors identified 37 controlled studies since 2005 evaluating the therapeutic effects of cannabinoids. The trials involved a total of 2,563 subjects.

Of the 37 clinical trials that have been recently conducted, eleven assessed the drug's impact on chronic neuropathic pain – a difficult to treat type of pain resulting from nerve damage. Other studies assessed the efficacy of cannabinoids to treat multiple sclerosis-associated spasticity (nine separate studies); HIV/AIDS (four); experimental pain (four); intestinal dysfunction (two); nausea/vomiting/appetite (two); schizophrenia (two); glaucoma (one); and 'other indications' (two).

Authors concluded, "Based on the clinical results, cannabinoids present an interesting therapeutic potential mainly as analgesics in chronic neuropathic pain, appetite stimulants in debilitating diseases (cancer and AIDS), as well as in the treatment of multiple sclerosis."

Last Wednesday investigators from the California Center for Medicinal Cannabis Research released the results of a series of double blind, placebo-controlled trials that determined that cannabinoids could be "a first-line treatment" for patients suffering from neuropathy.

Commenting on the review, NORML Deputy Director Paul Armentano said: "The safety and efficacy of marijuana as a medicine has now been established by the 'gold standard' of clinical study. Further, over 2,500 patients have used cannabinoids in controlled clinical trials over the past five years alone. This is a far greater total than the number of subjects that would likely be administered any other new drug pending United States FDA approval, and is a large enough population to once and for all establish marijuana's objective value as a medicine."

For more information, please contact Paul Armentano, NORML Deputy Director, at: paul@norml.org. Full text of the study, "Review of clinical studies with cannabis and cannabinoids 2005-2009," is available online from the International Association of Cannabinoid Medicines at: http://www.cannabis-med.org.
“Today’s scientists have substituted mathematics for experiments, and they wander off through equation after
equation, and eventually build a structure which has no relation to reality. ” -Nikola Tesla

"When the power of love overcomes the love of power the world will know peace." -Jimi Hendrix
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02-27-2010, 08:59 PM,
#2
RE: Over 2,500 Subjects Since 2005 Have Used Marijuana-Based Medicines In Controlled Clin
"This is a far greater total than the number of subjects that would likely be administered any other new drug pending United States FDA approval, and is a large enough population to once and for all establish marijuana's objective value as a medicine."

Unfortunately, this is is kind of misleading - the numbers average out to a little less than 70 people per study, which tends to be considered an incredibly small trial for the medical community in general. If all of those people had been in one or two studies, the above statement would be more persuasive, but numbers along those lines are what keeps the FDA from approving natural medicines all the time. That's because there's no money for studies that won't create the next patentable medication for a PhARMA company.

The real drug lords are the ones keeping us from effective medicine.
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