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Life Extension: Geneticists Discover a Way to Extend Lifespans to 800 Years
01-21-2010, 09:46 PM,
#1
Life Extension: Geneticists Discover a Way to Extend Lifespans to 800 Years
Quote:Geneticists Discover a Way to Extend Lifespans to 800 Years
Jan 16, 2008 01:30 PM
By Annalee Newitz

There is now a way to extend the lifespan of organisms so that humans could conceivably live to be 800 years old. In an amazing development, scientists at the University of Southern California have announced that they've extended the lifespan of yeast bacteria tenfold — and the recipe they used to do it might easily translate into humans. It involves tinkering with two genes, and cutting down your calorie intake. Tests have already started on people in Ecuador.

According to an announcement from PLoS Genetics:

Quote:Researchers have created baker's yeast capable of living to 800 in yeast years without apparent side effects. The basic but important discovery, achieved through a combination of dietary and genetic changes, brings scientists closer to controlling the survival and health of the unit of all living systems: the cell. "We're setting the foundation for reprogramming healthy life," says study leader Valter Longo of the University of Southern California.

Longo's group put baker's yeast on a calorie-restricted diet and knocked out two genes - RAS2 and SCH9 - that promote aging in yeast and cancer in humans.

"We got a 10-fold life span extension that is, I think, the longest one that has ever been achieved in any organism," Longo says. Normal yeast organisms live about a week.

"I would say 10-fold is pretty significant," says Anna McCormick, chief of the genetics and cell biology branch at the National Institute on Aging (NIA) and Longo's program officer. The NIA funds such research in the hope of extending healthy life span in humans through the development of drugs that mimic the life-prolonging techniques used by Longo and others, McCormick adds.

Baker's yeast is one of the most studied and best understood organisms at the molecular and genetic level. Remarkably, in light of its simplicity, yeast has led to the discovery of some of the most important genes and pathways regulating aging and disease in mice and other mammals.

Longo's group next plans to further investigate life span extension in mice. The group is already studying a human population in Ecuador with mutations analogous to those described in yeast.

"People with two copies of the mutations have very small stature and other defects," Longo says. "We are now identifying the relatives with only one copy of the mutation, who are apparently normal. We hope that they will show a reduced incidence of diseases and an extended life span."

Longo cautions that, as in the Ecuador case, longevity mutations tend to come with severe growth deficits and other health problems. Finding drugs to extend the human life span without side effects will not be easy.

I've always been a skeptic when it comes to life-extending research, but this has me rethinking my position.

Lifespan Extension [PLoS Genetics]
http://digg.com/general_sciences/Geneticists_Discover_a_Way_to_Extend_Lifespans_to_800_Years
http://io9.com/345728/geneticists-discover-a-way-to-extend-lifespans-to-800-years

I had thought that since extreme forms of life extension are well underway the goals of the elite are accelerating plans as many of them are nearing the end of their human existence. Since it is now fathomably attainable this could serve as the carrot for the accelerated pace of the development of this technology due to the personal stake of those involved in the financing and direction of this technology.

If this technology was more mainstream* this could instigate an extreme motivation and justification for those that seek to attain it through wealth and power. This could lead to a more cut-throat society in pursuit of this prize and for the driving fear of a natural death. Rationale in some would dictate a a no holds barred mentality in achieving this pinnacle to be a recipient of an extended planetary existence much like how health care is dangled today but more pronounced.

* To clarify what I meant by mainstream - It may be available to the public under a monopoly but only available for an enormous cost thus creating a unprecedented drive for wealth and status (permission) amongst those who desire to attain it.

The technology itself is probably well on its way, it's been under discussion 30 years if not longer. For example, I hear Rockefeller Sr. has a dialysis type device to filter impurities out of his blood embedded in him. Cancer has reportedly been cured since the 70s for select people through EM vibrational technologies. Body parts can be grown, manufactured etc.

Related:
History.Channel.Thats.Impossible... Eternal.Life.720p
http://concen.org/tracker/torrents-details.php?id=10988

Better Humans: The Politics of Human Enhancement and Life Extension
http://concen.org/tracker/torrents-details.php?id=13293
There are no others, there is only us.
http://FastTadpole.com/
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01-21-2010, 10:23 PM,
#2
RE: Life Extension: Geneticists Discover a Way to Extend Lifespans to 800 Years
if the gerontological holy grail is fast nearing possession by the super strata, then I think we can expect TSTHTF very soon - they want AI too - otherwise they won't really know the "mind of god"
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07-13-2010, 09:02 AM,
#3
RE: Life Extension: Geneticists Discover a Way to Extend Lifespans to 800 Years
Interesting film congruent with the topic.

Flight from Death -The Quest for Immortality (2003)



Now available on the tracker at http://concen.org/tracker/torrents-details.php?id=18232
There are no others, there is only us.
http://FastTadpole.com/
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07-13-2010, 01:01 PM,
#4
RE: Life Extension: Geneticists Discover a Way to Extend Lifespans to 800 Years
Heya whoa, back the fuck up to the throwaway line near the beginning of the article

Quote:Tests have already started on people in Ecuador.

Ima start searching now, but does anyone know anything more about this?

Could Ecuador be where some of the hitlers and mengeles etc fled to after ww2? Some of those suckers could conceivably be still alive hooked up to machines down there.


“I'm not from earth. I'm here on a research project. I'm preparing a paper on the psychosomatic ailments of pre-Apocalyptic condominium dwellers.”
-Sappho, Ash Ock

The Mushrooms once said to me "You must have a plan. If you don't have a plan, you will become part of someone else's plan."
-Terence McKenna
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07-13-2010, 01:12 PM,
#5
RE: Life Extension: Geneticists Discover a Way to Extend Lifespans to 800 Years
This is BLADE RUNNER, isn't it? THERE's the dystopia, right here. A pretty cool prediction, eh? Humanity is about to discover how moral it can be - or not.
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07-13-2010, 02:12 PM,
#6
RE: Life Extension: Geneticists Discover a Way to Extend Lifespans to 800 Years
Not much non life extension experiments in Ecuador except for testing and sampling the native population's DNA since they live a really long time. There was a lot of information that you could easily get with a google search about eating less to live a longer healthier life.

.. and then there was this article on life extension experiments performed on chickens.

Quote:Learn Life Extension Lessons from Chickens
Thursday, January 28, 2010
by: Kim Evans, citizen journalist

(NaturalNews) Beginning in 1912, Nobel Peace Prize winner Alexis Carrel kept chicken heart cells alive in a test tube for 34 years. It was an interesting experiment - especially because chickens generally only live three to five years. Those heart cells, however, far outlived even the chicken they came from. It was an experiment to prove Carrel's theory that cells are immortal given the right conditions, and he did this using a simple strategy. Every forty-eight hours, the mineralized water where the heart cells lived was changed, so the cells were always living in a clean, mineral-rich solution. After 34 years, and two years after Carrel's death, the experiment was purposely terminated. But the lessons about cell life - and life extension - are lasting.

Mineralized water is akin to the blood of the chicken - and of humans - and it's a dramatic testament to the results that can be achieved when the body and blood are mineralized and clean. Of course, it's also a testament to the consequences if they are not - and these days, the blood of most humans is far from clean. Our soils and therefore our bodies have also become mineral deplete.

One of the most common ways to collect filth in the body and blood is by having an unclean colon - a condition created when waste is not quickly and thoroughly eliminated. But according to holistic healer Dr. Bernard Jensen, most of the population suffers from constipation and doesn't know it. Dr. Jensen tells us that out of 300 autopsies performed at National College in Chicago - 285 of those people were constipated. Yet, according to those people's medical charts, only 15 said they were constipated and 285 claimed they weren't.

The biggest problem with infrequent eliminations is that it's impossible to have clean blood and a clean body with a dirty bowel. Many prominent holistic health professionals are very clear in saying that an unclean colon leaks filth to every cell and organ in the body. And when filth from the colon is throughout the body, you have the stage set for disease. Of course, with such filth throughout, colon cleansing also becomes just the beginning of the solution.

Dr. Jensen's findings provide a clue as to the level of cleanliness of most people's blood. Studies which have found hundreds of poisons in the average human's blood and even in the umbilical cord blood of infants provide another clue - and they've only tested for less than one percent of the chemicals in use.

Of course, the health of the general population is the biggest indicator of the cleanliness of the population's blood and body. So is the fact that 8 year-olds are getting dementia, heart disease, cancer, and kidney disease - all of which were once thought of as diseases related to aging. However, all of these diseases and more would be better understood as diseases related to having extreme amounts of toxicity in the body. It's just that these days, it's become easier and easier to achieve such a state, so more people are doing it in less and less time.

But, the question left unanswered is: What would human life expectancy really be if our blood and tissues were kept clean and our foods were mineral-rich? In a time of rampant chemical pollution and the destruction of our natural food supply, there's a chance we may never find out.

More:
Cleanse and Purify Thyself (book 1), Dr. Richard Anderson, N.D., N.M.D.

References:
http://www.corning.com/lifesciences/us_canada/en/about_us/cell_culture_history_1910.aspx
http://www.alenasites.com/alexis-carrel/
http://www.pbs.org/wnet/redgold/innovators/bio_carrel.html
http://www.ewg.org/minoritycordblood/home
http://www.naturalnews.com/026584_chemicals_cancer_blood.html
http://www.naturalnews.com/028040_life_extension_experiments.html


I have heard rumours that certain members of the Rockefeller family run blood dialysis machines that are inserted into their body which constantly clean and purify their blood and that they often get transfusions from younger folk. There are certain healing enzymes in younger blood that enhance regenerative capabilities. That kind of lends credence to vampires now doesn't it?

[Image: david_rockefeller-sr.jpg] [Image: bush-vampire.jpg]
There are no others, there is only us.
http://FastTadpole.com/
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07-13-2010, 04:54 PM,
#7
RE: Life Extension: Geneticists Discover a Way to Extend Lifespans to 800 Years
(07-13-2010, 01:01 PM)scaramanga667 Wrote: Heya whoa, back the fuck up to the throwaway line near the beginning of the article

Quote:Tests have already started on people in Ecuador.

Ima start searching now, but does anyone know anything more about this?

Could Ecuador be where some of the hitlers and mengeles etc fled to after ww2? Some of those suckers could conceivably be still alive hooked up to machines down there.
Icon_biggrin Maybe....
Remember Knowledge is the only thing THEY can't take from you, and Knowledge is Know how, and Know how is Power!!!

Live long and Prosper!!!! Have a plan beyond words, and worry not of why the storm is coming as to how you're going to survive in it!!!!

Deathanyl @gmail!!!!!!
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07-18-2010, 04:58 PM,
#8
RE: Life Extension: Geneticists Discover a Way to Extend Lifespans to 800 Years
Ecuador is now my long life future baby!! awsome topic most intriguing

Well thats intersting if cells live or last longer in a clean, mineral-rich solution. Then obviously now i understand why some water companies tell us to drink 8 glasses of water a day Tongue ! but then yet again most water is got more chlorine concentration which may lead to the road of zombie land.

Anyway to be frank theres ways of doing this, drinking water is one of them i dont know about everyone but when you drink a right amount of water a day you will realise that when you gotta go and urinate u will realise its white urine otherwise its yellow which clearly is a deposit of unclean blood cells or watever as described in this topic. Which means that our blood cells can be in a clean solution inside our internals, right?

The other way is fasting beleive it or not buttt its a big topic to talk about soo am just gonna mention it lol

I Was Born in a War & I Shall Die in a War

A Thug i am & A Thug Till am Gone
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07-18-2010, 09:40 PM,
#9
RE: Life Extension: Geneticists Discover a Way to Extend Lifespans to 800 Years
IMO we should keep the experimental results in perspective. They didn't extend life by 800 years. All they did was get a strain of yeast to live 10 times longer than it normally does and that is nowhere near 800 years. Yeast cultures are completely different events than human populations. There is no known correlation between significantly increasing the life spans of yeast and significantly increasing the life spans of humans.
An error does not become truth by reason of multiplied propagation, nor does truth become error because nobody sees it.
Mohandas Gandhi


Each of us is put here in this time and this place to personally decide the future of humankind.
Did you think you were put here for something less?
Chief Arvol Looking Horse
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07-18-2010, 10:14 PM,
#10
RE: Life Extension: Geneticists Discover a Way to Extend Lifespans to 800 Years
Quote:Which means that our blood cells can be in a clean solution inside our internals, right?

I doubt it it just means your piss is diluted. I (we) need to do more research. A look into the Chicken cell study and what concentration of whatever minerals were used would be a good start. Post your findings here. I'll do the same when time permits.
There are no others, there is only us.
http://FastTadpole.com/
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07-19-2010, 10:33 AM,
#11
RE: Life Extension: Geneticists Discover a Way to Extend Lifespans to 800 Years
Hi!
Southern California University have declared that they've extended the lifespan of 800 of yeast bacteria and it may easily work on humans. In Ecuador the testing had been already started which doesn't have any side effects.
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07-19-2010, 03:13 PM,
#12
RE: Life Extension: Geneticists Discover a Way to Extend Lifespans to 800 Years
I don't beleef you annyjoseph - cut the preamble and get that spamlink in your sig already so we can do the inevitable. Smile
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04-04-2011, 11:16 PM,
#13
Rainbow  Increasing Your Life Expectancy: Modern Medicine’s Impact on the Extension of Life
Increasing Your Life Expectancy: Modern Medicine’s Impact on the Extension of Life

Dr. Peter Dingle

All too often, we hear that the reason life expectancy has been increased is thanks to the marvellous developments in modern medicine. This is a message that is repeated many times and promoted by the medical industry – with little or no evidence.

In fact, the opposite may be the truth. A combination of not understanding the concept of life expectancy, ignoring scientific facts, plus a willingness to take credit when it is not due has seen the medical industry promote itself as the reason we live longer. Behind the scenes, this is little more than a marketing strategy for the big pharmaceutical companies.

Don’t get me wrong; this does not undermine the fantastic role medical doctors play in acute life-saving events. These make a huge contribution to an individual’s life expectancy but make an insignificant contribution to life expectancy for all of us.

The overemphasis of modern medicine on the pharmaceutical model and “silver bullet” approach has led to a disempowerment of individuals over their own health during the past few decades, during which we have seen a huge rise in chronic illness. The more specialists and the bigger the medical budget, the poorer the health of the public.

Let’s take an example: the US uses 50% of the world’s pharmaceuticals and spends more per person on medicine than any other nation, yet has one of the poorest health outcomes in the developed world.

Modern medicine tends to focus on prescriptive treatment of disease, rather than health promotion, prevention and management.1,2 It is likely that everyday medical care provides little contribution to increased life expectancy of a population.3,4

Gains in life expectancy worldwide have been greater during last century than at any other time in recorded history.5,6 Statistical analyses show that since the early 1800s life expectancy at birth has seen a linear rate of increase.7
Within this time, it has been human advances in sanitation, increased food supply, improved access to water, and basic preventative medicine that have helped drive these steady increases in the developed world – not pharmaceuticals. The majority of life expectancy gains were made before pharmaceuticals to treat heart attack, stroke and other forms of chronic illness were even developed.

However, it is important to understand the concept of life expectancy. It is the average number of years of life remaining at a given age for a selected population. Life expectancy at birth is commonly used as the main indicator of human health and well-being. It is said to give an indication of the overall mortality of a population.5 However, it is a poor indicator of population health.8

Life expectancy is poorly understood. Most people think it is increasing the age to which they can live; for example, people at 50 think that they are going to live longer because of an increase in life expectancy. This is not the case. Life expectancy is a statistical anomaly, which takes the average of the age of a person’s death. It includes everyone: infants, children, teenagers right through to those in their old age. This means that if the rates of infant mortality are reduced, the average life expectancy is dramatically increased overall.

A simple example will highlight this. If 50% of the population died before one year of age and 50% of the population died at 80 years of age, the average age of life expectancy is around 40 years even though 50% lived to 80 years of age. If you eliminate the infant mortality the life expectancy goes up to 80 years of age. This does not mean people are living longer, they are still dying at 80 years of age but the statistical average, the “life expectancy,” has increased.

This reduction of child mortality skews the life expectancy.9 Statistical analysis has revealed that the trends in cohort geriatric mortality follow those of reducing childhood mortality.10 This means that benefits from improvements in mortality rates of younger generations provide a false impression of the benefits to older generations. Furthermore, life expectancy at birth can only predict life expectancy with 95% confidence to within a fourteen-year range.9

That is, we may live to 80 years of age plus or minus 14 years. Therefore it cannot be trusted as a reliable base to measure contribution of health interventions for whole population life expectancy. Reduced child mortality positively skews life expectancy statistics and gives the misconception of increased population lifespan.11,9,6

To highlight the problems with this approach even further, the high rate of infant mortality in the 1900s was a result of the advent of pathological anatomy in the 1820s, and consequently the increase in number of conducted autopsies, is correlated to the incidence of fatal childbed fever. The decline in the 1840s and 1850s was a result of hygiene practices that the medical profession battled against for two decades. Why did it take so long?

Continue to read:
http://www.newdawnmagazine.com/articles/increasing-your-life-expectancy
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04-05-2011, 04:54 AM,
#14
RE: Life Extension: Geneticists Discover a Way to Extend Lifespans to 800 Years
Related:

Pro life extension technology film
Promoted by Alex Jones a few years ago
http://concen.org/forum/showthread.php?tid=16696

Exploring Life Extension
[video=googlevideo]http://video.google.co.uk/videoplay?docid=6581761732541483047[/video]

Torrent: Better Humans? Bioethics Human Enhancement Life Extension Technology Pack (Books and Articles)
http://concen.org/forum/showthread.php?tid=33942
http://concen.org/tracker/torrents-details.php?id=18237

Telomeres and life extension?
Q & A Discussion Thread
http://concen.org/forum/showthread.php?tid=5755

Tests raise life extension hopes
A Nature Magazine Article and a BBC Column
http://concen.org/forum/showthread.php?tid=2246
There are no others, there is only us.
http://FastTadpole.com/
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04-22-2011, 04:55 PM,
#15
RE: Life Extension: Geneticists Discover a Way to Extend Lifespans to 800 Years
I also heard that kind of story from my teacher and I am not believing it but from all the above discussion I am convinced that it is possible. But what a human do for 800 years and what is the benefit of this research?
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